Anti-HUMAN IRAK4 (C-TERMINAL)

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• Catalog number
  MBS223396
• Price:

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• Size
  100ug

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• Alternative name1
  Anti-RABBIT ANTI HUMAN IRAK4 (C-TERMINAL)
• Alternative name2
  RABBIT ANTI HUMAN IRAK4 (C-TERMINAL)
• Alternative name3
  Lapin ANTI Homo sapiens IRAK4 (C-TERMINAL)
• Alternative name4
  IRAK4
• Alternative name5
  N/A
• Other names
  interleukin-1 receptor-associated kinase 4 isoform a; Interleukin-1 receptor-associated kinase 4; interleukin-1 receptor-associated kinase 4; renal carcinoma antigen NY-REN-64; interleukin-1 receptor-associated kinase 4; Renal carcinoma antigen NY-REN-64
• Gene name
  IRAK4
• Gene name synonims
  N/A
• Other gene names
  IRAK4; IRAK4; IPD1; REN64; IRAK-4; NY-REN-64; IRAK-4
• Category
  Antibodies
• Clonality
  Polyclonal
• Immunoglobulin isotype
  Polyclonal IgG
• Clone
  Polyclonal antibody
• Host organism
  Rabbit
• Species reactivity
  Human
• Specificity and cross reactivity
  IRAK4 This item detects an epitope within the C-terminal (CT) region of integrin-1 receptor-associated kinase 4 (IRAK4). IRAK4 has a molecular weight of 50kD, and is an important mediator in the signal transduction of Toll-like receptor (TLR) and interleukin-1 (IL-1) receptor family members. IRAK4 functions in this signal transduction pathway by binding to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signalling cascades leading to transcriptional up-regulation and mRNA stabilization. _x000D__x000D_IRAK4 is a key activator of TLR-mediated signal transductions and has crucial roles in innate immune responses. It is expressed by the liver, kidneys and skeletal muscle.
• Purification method
  N/A
• Form Appearance
  Purified (Purified IgG - liquid)
• Concentration
  IgG concentration 1.0mg/ml
• Storage and shipping
  Store at +Store productone at +4 degrees Celsius. or productone should be stored at -20 degrees Celsius. if preferred. Storage in frost-free freezers is not recommended. productone should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should productone contain a precipitate we recommend microcentrifugation before use. Shelf Life: 18 months from date of dispatch.
• Tested for
  Immunohistology - Frozen (IHC), Western Blot (WB)
• Description
  productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against. Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in. Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, they are inexpensive to manufacture and respectively to buy, the time needed for production is considerably shorter. Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions. To obtain more detailed information on productone, please, refer to the full product datasheet.
• Advisory
  In order to retain the quality and the affinity of productone unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Test
  MBS Polyclonals supplies antibodies that are for research of human proteins.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

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• Gene target
  IRAK4  
• Gene symbol
  IRAK4
• Short name
  Anti- IRAK4 (C-TERMINAL)
• Technique
  anti-Human, anti-, anti, antibody to, antibodies, antibodies against human proteins
• Species
  Human, Humans
• Alternative name
  Antibody toHUMAN interleukin-1 receptor-associated kinase 4 (C-TERMINAL)
• Alternative technique
  antibodies
• Alternative to gene target
  interleukin-1 receptor-associated kinase 4, IRAK4 and IDBG-28022 and ENSG00000198001 and 51135, transferase activity, Extracellular, Irak4 and IDBG-177236 and ENSMUSG00000059883 and 266632, IRAK4 and IDBG-633310 and ENSBTAG00000021105 and 533692

Gene info

• Identity
  HGNC:17967
• Gene
  IRAK4
• Long gene name
  interleukin 1 receptor associated kinase 4
• Synonyms
  • NY-REN-64
• GenBank acession
  • AF155118
• Locus
  12q12
• Discovery year
  2002-09-27
• Entrez gene record
  51135
• Pubmed identfication
  • 3772297
  • 10508479
• VEGA ID
  OTTHUMG00000169425
• Locus Specific Databases
  • IRAK4base: Mutation registry for IRAK4 deficiency
  • LRG_75

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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