NELL2 Recombinant Protein

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• Catalog number
  95-113
• Price:

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• Size
  0.05 mg

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• About recombinant protein
  NELL2 is a neuron-specific thrombospondin-1-like extracellular protein containing six epidermal growth factor-like domains (1). It is highly expressed in the hippocampus in vivo (2) and promotes survival of rat primary cultured neurons through activation of JNK and suppression of ERK (3). As ERK is required for the induction of hippocampal long term potentiation (LTP) and JNK appears to be inhibitory on LTP (4,5), it had been suggested that NELL2 may play a role in synaptic plasticity. More recently, NELL2 has been shown to promote differentiation of motor and sensory neurons and stimulates mitogenesis of dorsal root ganglia in chickens (6).
• Other name of the recombinant
  NELL2 Recombinant Protein: mel91, R75516, A330108N19Rik
• Recombinant in
  E. coli
• His tag on the recombinant protein
  Fusion Partner: C-terminal His-tag
• SEQUENCE
  aa 22 - 238
• Activity
  not available
• Use of recmbinant
  This recombinant protein can be used for WB, ELISA, MS and neutralization assays. For research use only.
• Protein is used in
  E, WB, MS
• Suspention medium
  100mM sodium phosphate, 10mM Tris, 500mM NaCl, 25 mM imidazole, 2mM MgCl2, 10% gycerol
• Keep at
  Store in working aliquots at -70˚C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  2494290
• Accession nr
  Q61220
• KDa of reombinant
  28 kDa (Calculated)
• Pureity
  ~95%
• About
  Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
• Protein s origin
  Mouse
• Vial
  Liquid
• NCBI ID
  54003
• Gene name
  NEL-like 2
• Source
  Mus musculus
• Uniprot
  Q61220
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

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• Gene target
  NELL2   Protein  
• Gene symbol
  Nell2
• Short name
  NELL2 Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  NEL-like 2 (chicken) Rec. Protein
• Alternative technique
  rec
• Alternative to gene target
  NEL-like 2 (chicken), NRP2, NELL2 and IDBG-28191 and ENSG00000184613 and 4753, protein binding, Extracellular, Nell2 and IDBG-177541 and ENSMUSG00000022454 and 54003, NELL2 and IDBG-633287 and ENSBTAG00000032183 and 524622

Gene info

• Identity
  HGNC:7751
• Gene
  NELL2
• Long gene name
  neural EGFL like 2
• Synonyms gene name
  • nel (chicken)-like 2
  • NEL-like 2 (chicken)
• Synonyms
  • NRP2
• GenBank acession
  • D83018
• Locus
  12q12
• Discovery year
  1996-07-17
• Entrez gene record
  4753
• Pubmed identfication
  • 8975702
  • 25537860
• RefSeq identity
  • NM_006159
• VEGA ID
  OTTHUMG00000169464

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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